{"id":33722,"date":"2022-11-26T11:10:48","date_gmt":"2022-11-26T11:10:48","guid":{"rendered":"https:\/\/gyncentrum.pl\/mikrobiom\/endobiome-mikrobiom-endometrium\/"},"modified":"2024-02-21T09:54:44","modified_gmt":"2024-02-21T09:54:44","slug":"endobiome-endometrial-microbiome","status":"publish","type":"servies","link":"https:\/\/gyncentrum.pl\/en\/microbiome\/endobiome-endometrial-microbiome\/","title":{"rendered":"ENDObiome &#8211; endometrial microbiome"},"content":{"rendered":"\n<section id=\"simple-hero-block_858a7585fbd397c49ab3039d5d9809cf\" class=\"block-simple-hero  \">\n    <div class=\"container\">\n        <h3 class=\"title\">ENDObiome &#8211; endometrial microbiome<\/h3>\n        <div class=\"circle style-element\"><\/div>\n        <img decoding=\"async\" class=\"cross style-element\" src=\"https:\/\/gyncentrum.pl\/wp-content\/themes\/gyn-centrum\/img\/orange-cross.svg\" width=\"21\" height=\"21\" alt=\"\" title=\"\">\n        <div class=\"square style-element\"><\/div>\n    <\/div>\n<\/section>\n\n\n\n            <div class=\"container breadcrumbs-container custom-breadcrumbs-wrapper\">\n                <span>\n                    <span>\n                        <a href=\"https:\/\/gyncentrum.pl\/en\/\" class=\"home-link\">Home<\/a>\n                        <img decoding=\"async\" src=\"https:\/\/gyncentrum.pl\/wp-content\/themes\/gyn-centrum\/img\/breadcrumbs-arrow.svg\" class=\"breadcrumbs-separator\" alt=\"\" title=\"\">\n                        <span>\n                                                                <a href=\"https:\/\/gyncentrum.pl\/en\/microbiome\/\">Microbiome<\/a>\n                                    <img decoding=\"async\"\n                                        src=\"https:\/\/gyncentrum.pl\/wp-content\/themes\/gyn-centrum\/img\/breadcrumbs-arrow.svg\"\n                                        class=\"breadcrumbs-separator\">\n                                                                <span class=\"breadcrumb_last\"\n                                  aria-current=\"page\">ENDObiome &#8211; endometrial microbiome<\/span>\n                        <\/span>\n                    <\/span>\n                <\/span>\n            <\/div>\n\n            \n\n\n<section id=\"breadcrumbs-block_02f0b37de23895dfdc57da1e7aeb601c\" class=\"block-breadcrumbs \">\n    \n            <div class=\"container breadcrumbs-container \">\n                <span>\n                    <span>\n                        <a href=\"https:\/\/gyncentrum.pl\/en\/\" class=\"home-link\">Home<\/a>\n                        <img decoding=\"async\" src=\"https:\/\/gyncentrum.pl\/wp-content\/themes\/gyn-centrum\/img\/breadcrumbs-arrow.svg\" class=\"breadcrumbs-separator\" alt=\"\" title=\"\">\n                        <span>\n                                                                <a href=\"https:\/\/gyncentrum.pl\/en\/microbiome\/\">Microbiome<\/a>\n                                    <img decoding=\"async\"\n                                        src=\"https:\/\/gyncentrum.pl\/wp-content\/themes\/gyn-centrum\/img\/breadcrumbs-arrow.svg\"\n                                        class=\"breadcrumbs-separator\">\n                                                                <span class=\"breadcrumb_last\"\n                                  aria-current=\"page\">ENDObiome &#8211; endometrial microbiome<\/span>\n                        <\/span>\n                    <\/span>\n                <\/span>\n            <\/div>\n\n            <\/section>\n\n\n\n<section id=\"content-block_81dbaa62832562fe71316259d5ab8d57\" class=\"block-content image-right   \">\n        <div class=\"container\">\n        <div class=\"text-part\">\n            <div class=\"subtitle-wrapper\">\n                <div class=\"icon-wrapper\">\n                    <img decoding=\"async\" width=\"42\" height=\"41\" src=\"https:\/\/gyncentrum.pl\/wp-content\/uploads\/2022\/10\/orange-sketchy-heart.svg\" class=\"subtitle-icon lazyload\" alt=\"\" title=\"\">\n                <\/div>\n                <span class=\"subtitle text--t3\"><\/span>\n\n            <\/div>\n            <h3 class=\"title\"><p>Study to assess the composition of the endometrial microbiome<\/p>\n<\/h3>\n            <div class=\"text text--t1\"><p>Are you trying to have a baby? Are you preparing for an in vitro procedure? Have you experienced miscarriages? Do you have frequent intimate infections or chronic endometritis? Perform ENDObiome &#8211; a test that evaluates the composition of the endometrial microbiome and get a chance for successful treatment, pregnancy and childbirth.<\/p>\n<\/div>\n            \n        <\/div>\n                    <div class=\"image-part\">\n                <img decoding=\"async\" class=\"heart-dust\" src=\"https:\/\/gyncentrum.pl\/wp-content\/themes\/gyn-centrum\/img\/orange-sketchy-heart-empty.svg\" width=\"28\" height=\"50\" alt=\"\" title=\"\">\n                <img decoding=\"async\" class=\"heart-dust-crocked\" src=\"https:\/\/gyncentrum.pl\/wp-content\/themes\/gyn-centrum\/img\/orange-sketchy-crocked-heart.svg\" width=\"42\" height=\"37\" alt=\"\" title=\"\">\n                <div class=\"dust dust-1\"><\/div>\n                <div class=\"dust dust-2\"><\/div>\n                <div class=\"dust dust-3 orange\"><\/div>\n                <div class=\"dust dust-4\"><\/div>\n                <div class=\"dust dust-5\"><\/div>\n                <div class=\"dust dust-6 orange\"><\/div>\n                <img decoding=\"async\" width=\"1251\" height=\"657\" src=\"https:\/\/gyncentrum.pl\/wp-content\/uploads\/2022\/11\/endobiome-en.png\" class=\"side-image lazyload\" alt=\"\" srcset=\"https:\/\/gyncentrum.pl\/wp-content\/uploads\/2022\/11\/endobiome-en.png 1251w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2022\/11\/endobiome-en-768x403.png 768w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2022\/11\/endobiome-en-200x105.png 200w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2022\/11\/endobiome-en-930x488.png 930w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2022\/11\/endobiome-en-480x252.png 480w\" sizes=\"(max-width: 1251px) 100vw, 1251px\" title=\"\">            <\/div>\n                <\/div>\n<\/section>\n\n\n\n    <section id=\"spacer-block_762959cda331af821db23b09f96696bc\"\n             class=\"block-spacer  height-32px background-transparent\">\n    <\/section>\n\n\n\n\n<section id=\"simplest-cta-block_f17b5ffd2694ec40efcc816ec467a94f\" class=\"block-simplest-cta  color-style-dark \">\n    <div class=\"container\">\n        <div class=\"inner-wrapper\">\n                            <div class=\"icon-wrapper\">\n                    <img decoding=\"async\" width=\"42\" height=\"41\" src=\"https:\/\/gyncentrum.pl\/wp-content\/uploads\/2022\/10\/orange-sketchy-heart.svg\" class=\"icon lazyload\" alt=\"\" title=\"\">\n                <\/div>\n                                <h3 class=\"title\"><p>Get your endometrial microbiome tested!<br \/>\nGain the chance for successful treatment and pregnancy and childbirth<\/p>\n<\/h3>\n                                <div class=\"text\"><\/div>\n                            <div class=\"contact-wrapper\">\n                                    <a class=\"phone-link\" href=\"tel:+48600466592\">\n                        <img decoding=\"async\" src=\"https:\/\/gyncentrum.pl\/wp-content\/themes\/gyn-centrum\/img\/phone-icon.svg\" alt=\"phone\" height=\"32\" width=\"33\" title=\"\">\n                        <span class=\"number\">+48 600 466 592<\/span>\n                    <\/a>\n                                                        <a class=\"email-address\" href=\"mailto:office@gyncentrum.pl\">\n                        <img decoding=\"async\" src=\"https:\/\/gyncentrum.pl\/wp-content\/themes\/gyn-centrum\/img\/mail-box.svg\" alt=\"phone\" height=\"22\" width=\"32\" title=\"\">\n                        <span class=\"address\">office@gyncentrum.pl<\/span>\n                    <\/a>\n                                <\/div>\n        <\/div>\n\n    <\/div>\n<\/section>\n\n\n\n<section id=\"conent-2-block_83c3d0465dc80c1c77f0e72e18ba9198\" class=\"block-conent-2  image-type-container-width  \">\n        <div class=\"container \">\n                <div class=\"columns-wrapper\">\n            <div class=\"single-column\">\n                            <h3 class=\"title\"><p>ENDObiome &#8211; analysis of the endometrial microbiome met. NGS<\/p>\n<\/h3>\n                            <span class=\"text text--t1\"><p><strong>ENDObiome is a screening test that provides complete information on the microbial environment of the uterus.<\/strong> A balanced endometrial microbiome is an important factor in a woman&#8217;s intimate health, as well as successful embryo implantation and a normal pregnancy.<\/p>\n<p>The test is performed using the Next Generation Sequencing (NGS) technique. The technique is based on sequencing the V3 and V4 subunits of the bacterial 16s rRNA gene, which makes it possible to accurately identify bacteria to genus and species. <strong>Examination of the microbiome by the NGS technique, unlike traditional microbiological methods, makes it possible to know the full battery profile of the endometrium, taking into account non-culturable strains as well, and allows to determine the percentage of bacteria identified in the sample.<\/strong><\/p>\n<\/span>\n                            <\/div>\n                            <div class=\"single-column\">\n                                            <span class=\"text text--t1\"><p>The normal microbiome of the uterine environment, <strong>like that of the vagina, is dominated by Lactobacillus,<\/strong> the so-called lactic acid bacilli. This bacterium accounts for more than 30% of the total endometrial microbiome. Other bacteria residing on the surface of the endometrium are: Acinetobacter (9.07%), Pseudomonas (9.09%), Sphingobium (5%) and Vagococcus (7.29%) [1]. <strong>The presence of the above microorganisms in the right proportions is extremely important for a woman&#8217;s health and fertility.<\/strong><\/p>\n<p>Microbial balance provides protection against pathogen attack and enables the proper functioning of a woman&#8217;s reproductive system. Dysbiosis, on the other hand, is a disruption of the quantitative relations between microorganisms, often in favor of pathogenic bacteria. <em>An abnormal endometrial microflora can impede embryo implantation, lead to pregnancy loss and premature delivery, and be associated with gynecological and obstetric conditions,<\/em> i.e. chronic endometrial inflammation, intimate infections and even cancer of the reproductive organs.<\/p>\n<\/span>\n                                        <\/div>\n                        <\/div>\n\n    <\/div>\n<\/section>\n\n\n\n    <section id=\"spacer-block_a07ade9593498fe2e1c5113dc8effea1\"\n             class=\"block-spacer  height-64px background-transparent\">\n    <\/section>\n\n\n\n\n<section id=\"cta-banner-block_0b86204241ab9b4cfb97d00a1a84477b\"\n         class=\"block-cta-banner \">\n            <div class=\"background-wrapper\">\n            <img decoding=\"async\" width=\"2560\" height=\"1584\" src=\"https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-scaled.jpg\" class=\"desktop-image background lazyload\" alt=\"\" srcset=\"https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-scaled.jpg 2560w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-768x475.jpg 768w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-1920x1188.jpg 1920w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-200x124.jpg 200w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-1536x951.jpg 1536w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-2048x1267.jpg 2048w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-930x576.jpg 930w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-480x297.jpg 480w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" title=\"\">            <img decoding=\"async\" width=\"2560\" height=\"1584\" src=\"https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-scaled.jpg\" class=\"mobile-image background lazyload\" alt=\"\" srcset=\"https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-scaled.jpg 2560w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-768x475.jpg 768w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-1920x1188.jpg 1920w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-200x124.jpg 200w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-1536x951.jpg 1536w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-2048x1267.jpg 2048w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-930x576.jpg 930w, https:\/\/gyncentrum.pl\/wp-content\/uploads\/2024\/02\/aerial-view-of-wawel-castle-in-krakow-poland-480x297.jpg 480w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" title=\"\">        <\/div>\n            <div class=\"container\">\n                <div class=\"content-wrapper\">\n                            <span class=\"subtitle text--t3\">Let&#8217;s meet in Cracow!<\/span>\n                            <h3            class=\"title\">Visit our Cracow Clinic        <\/h3>\n                    <div class=\"text text--t1\"><p>You want to learn more about our clinic?<\/p>\n<p>Don&#8217;t wait and and combine visiting our clinic with sightseeing around the Cracow.<\/p>\n<p>Click here, and schedule an appointment.<\/p>\n<\/div>\n                    <div class=\"button-row\">\n                    <a class=\"fz-button  new-button-style new-color-style-orange-100 new-fill-style-full\" href=\"https:\/\/gyncentrum.pl\/en\/gyncentrum-clinics\/gyncentrum-cracow\/\">\n        \n        <span class=\"text-itself\">Find out more<\/span>\n\n                <\/a>\n                <\/div>\n    <\/div>\n\n    <\/div>\n<\/section>\n\n\n\n<section id=\"conent-2-block_b1a4769c850bc05df09bd0325c09d88f\" class=\"block-conent-2  image-type-container-width  \">\n        <div class=\"container \">\n                <div class=\"columns-wrapper\">\n            <div class=\"single-column\">\n                            <h3 class=\"title\"><p>ENDObiome &#8211; for whom?<\/p>\n<\/h3>\n                            <span class=\"text text--t1\"><p>Testing the endometrial microbiome is recommended especially for women who:<\/p>\n<ul>\n<li>are preparing for the in vitro fertilization procedure<\/li>\n<li>have experienced failures of the in vitro procedure due to problems with embryo implantation<\/li>\n<li>have experienced multiple miscarriages<\/li>\n<li>are having difficulty getting pregnant<\/li>\n<li>have experienced premature births<\/li>\n<li>have a diagnosis of endometriosis<\/li>\n<li>suffer from frequent intimate infections or chronic inflammation of the reproductive organs<\/li>\n<\/ul>\n<\/span>\n                            <\/div>\n                    <\/div>\n\n    <\/div>\n<\/section>\n\n\n\n<section id=\"conent-2-block_9980a6a3cbcbec77f6907e239228690f\" class=\"block-conent-2  image-type-container-width  \">\n        <div class=\"container \">\n                <div class=\"columns-wrapper\">\n            <div class=\"single-column\">\n                            <h3 class=\"title\"><p>Why perform an ENDObiome?<\/p>\n<\/h3>\n                            <span class=\"text text--t1\"><ul>\n<li><strong>ENDObiome<\/strong> allows assessment of the proportion of individual Lactobacillus species in the endometrial microbiota. When the result indicates dysbiosis or the presence of pathogenic species, the doctor can suggest appropriate treatment with antibiotics and\/or probiotics.<\/li>\n<li><strong>ENDObiome<\/strong> identifies the presence of pathogenic bacteria responsible for chronic endometritis, which is often asymptomatic and not detectable on ultrasound.<\/li>\n<li><strong>ENDObiome<\/strong> increases the effectiveness of in vitro fertilization. The test helps determine whether the microbial environment of the uterus is optimal for embryo implantation. This allows the doctor to make an informed decision on whether to transfer the embryo or postpone it and initiate treatment to restore a normal microbiota.<\/li>\n<li>The<strong>ENDObiome<\/strong> gives a complete picture of the endometrial microbial profile, making it possible to modify the microflora with diet, appropriate supplementation or antibiotic therapy. This, in turn, increases the chance of embryo implantation, normal pregnancy and childbirth.<\/li>\n<\/ul>\n<\/span>\n                            <\/div>\n                    <\/div>\n\n    <\/div>\n<\/section>\n\n\n<div class=\"container\">\n<p><strong>Sources:<br>[1] B. Macura, M. Majewska-Szczepanik, A.Strz\u0119pa, M. Szczepanik, Influence of the uterine microbiota on the health of a woman and her offspring, General Medicine and Health Sciences 2020, Vol. 26, No. 3, pp. 230-239.<\/strong><\/p>\n<\/div>\n\n\n    <section id=\"pop-up-block_1010623e706a07b4b0cba539815ea5fe\"\n             class=\"block-pop-up  type-halfbyhalf color-style-light\">\n        <div id=\"first-visit-infertility-newv1\" class=\"pop-up closed\">\n            <div class=\"container\">\n                <div class=\"inner-wrapper\">\n                    <img decoding=\"async\" src=\"https:\/\/gyncentrum.pl\/wp-content\/themes\/gyn-centrum\/img\/close-cross.svg\" alt=\"\" class=\"close-cross lazyload\" width=\"12\" height=\"12\" title=\"\">\n\n                    <div class=\"content-wrapper\">\n\n                                                <h2                        class=\"title\"><p>Schedule a<strong> <span style=\"color: orange;\">\u00a0consultation <\/span><\/strong>with our specialist!<\/p>\n                    <\/h2>\n                                            <div class=\"text\"><\/div>\n                                            <div class=\"contact-wrapper\">\n                                                    <a class=\"phone-link\" href=\"tel:+48600466592\">\n                                <img decoding=\"async\" src=\"https:\/\/gyncentrum.pl\/wp-content\/themes\/gyn-centrum\/img\/phone-icon.svg\" alt=\"phone\" height=\"32\" width=\"33\" title=\"\">\n                                <span class=\"number\">+48 600 466 592<\/span>\n                            <\/a>\n                                                                        <\/div>\n                <\/div>\n\n\n                                    <div class=\"form-wrapper\">\n                        \n<div class=\"wpcf7 no-js\" id=\"wpcf7-f40917-o1\" lang=\"pl-PL\" dir=\"ltr\" data-wpcf7-id=\"40917\">\n<div class=\"screen-reader-response\"><p role=\"status\" aria-live=\"polite\" aria-atomic=\"true\"><\/p> <ul><\/ul><\/div>\n<form action=\"\/en\/wp-json\/wp\/v2\/servies\/33722#wpcf7-f40917-o1\" method=\"post\" class=\"wpcf7-form init cf7mls-no-scroll cf7mls-no-moving-animation\" aria-label=\"Formularz kontaktowy\" novalidate=\"novalidate\" data-status=\"init\">\n<fieldset class=\"hidden-fields-container\"><input type=\"hidden\" name=\"_wpcf7\" value=\"40917\" \/><input type=\"hidden\" name=\"_wpcf7_version\" value=\"6.1.5\" \/><input type=\"hidden\" name=\"_wpcf7_locale\" value=\"pl_PL\" \/><input type=\"hidden\" name=\"_wpcf7_unit_tag\" value=\"wpcf7-f40917-o1\" \/><input type=\"hidden\" name=\"_wpcf7_container_post\" value=\"0\" \/><input type=\"hidden\" name=\"_wpcf7_posted_data_hash\" value=\"\" \/><input type=\"hidden\" name=\"_wpcf7cf_hidden_group_fields\" value=\"[]\" \/><input type=\"hidden\" name=\"_wpcf7cf_hidden_groups\" value=\"[]\" \/><input type=\"hidden\" name=\"_wpcf7cf_visible_groups\" value=\"[]\" \/><input type=\"hidden\" name=\"_wpcf7cf_repeaters\" value=\"[]\" \/><input type=\"hidden\" name=\"_wpcf7cf_steps\" value=\"{}\" \/><input type=\"hidden\" name=\"_wpcf7cf_options\" value=\"{&quot;form_id&quot;:40917,&quot;conditions&quot;:[],&quot;settings&quot;:{&quot;animation&quot;:&quot;yes&quot;,&quot;animation_intime&quot;:200,&quot;animation_outtime&quot;:200,&quot;conditions_ui&quot;:&quot;normal&quot;,&quot;notice_dismissed&quot;:false,&quot;notice_dismissed_update-cf7-5.8.6&quot;:true}}\" \/><input type=\"hidden\" name=\"Service\" value=\"ENDObiome &#8211; 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A balanced endometrial microbiome is an important factor in a woman&#8217;s intimate health. <\/p>\n","protected":false},"featured_media":0,"parent":33718,"menu_order":342,"template":"","class_list":["post-33722","servies","type-servies","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/gyncentrum.pl\/en\/wp-json\/wp\/v2\/servies\/33722","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gyncentrum.pl\/en\/wp-json\/wp\/v2\/servies"}],"about":[{"href":"https:\/\/gyncentrum.pl\/en\/wp-json\/wp\/v2\/types\/servies"}],"version-history":[{"count":8,"href":"https:\/\/gyncentrum.pl\/en\/wp-json\/wp\/v2\/servies\/33722\/revisions"}],"predecessor-version":[{"id":35147,"href":"https:\/\/gyncentrum.pl\/en\/wp-json\/wp\/v2\/servies\/33722\/revisions\/35147"}],"up":[{"embeddable":true,"href":"https:\/\/gyncentrum.pl\/en\/wp-json\/wp\/v2\/servies\/33718"}],"wp:attachment":[{"href":"https:\/\/gyncentrum.pl\/en\/wp-json\/wp\/v2\/media?parent=33722"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}